The Tambopata National Reserve and surrounding rainforest areas are located next to Puerto Maldonado, a small town in south-eastern Peru close to the border with Bolivia.
To get there, most people take flights to Puerto Maldonado from Cusco (near Machu Picchu) or Lima, take a bus from Cusco or come on a bicycle tour. See How to Get to Puerto Maldonado for detailed information on various travel options.
From Puerto Maldonado, getting to the rainforest will depend on the location of your accommodation and the services they offer.
Some lodgings can be reached by mototaxi, an adapted three-wheeled motorbike rickshaw. This form of transport is very cheap and you will find them all over town, at the airport and near the bus station. Alternatively, your accommodation may arrange a pick-up service from the airport or bus station for you (included with lodging or for a surcharge).
By mototaxi, the airport is about 20 minutes and the bus station 10 minutes to the main square in Puerto Maldonado, the Plaza de Armas.
Most of the Amazon rainforest lodges will entail a mototaxi ride or pick-up service from the airport or bus station to the centre of Puerto Maldonado and then a boat ride to your lodge. The pick-up at the airport / bus station and the boat transfer to the lodge might be included with your booking – check this before booking.